A biomimetic, transseptal chordal replacement therapy designed to restore natural anatomy and deliver surgical-quality repair with a minimal footprint.
TMVr
Transcatheter Mitral Valve Repair
With Transcatheter Mitral Valve Repair (TMVr), a new treatment paradigm has been established during the last decade. This new kind of procedure places a structural implant via a tube (transcatheter) into the targeted heart valve. The catheter is inserted through a small incision at the groin and moved along the blood vessels. After placing the structural repair implant through the catheter, the delivery mechanism is withdrawn through the same blood vessel. This delivery approach eliminates the need for a surgical procedure to open the heart, shifting the "Gold Standard" from heart surgery to interventional cardiology.
The obvious advantages to the patient, such as less trauma and reduced hospital stay, have resulted in fast adoption of TMVr: introduced barely a decade ago, approximately 50,000 patients chose TMVr over surgery in 2020.
CHORDA REPLACEMENT
The structure of a mitral valve comprises two valve leaflets connected on top by the annular ring. On the lower end, the valve leaflets are connected to a muscle structure (the papillary muscles) via the mitral chord threads (mitral valve chords, mitral chords or chordae). Elongation or rupture of mitral valve chords is a frequent structural damage and a key cause of leaflet prolapse and MR. Approximately 60% of isolated mitral valve surgeries performed in the United States are for patients with leaflet prolapse with elongated or ruptured mitral chords.
Replacement of ruptured chordae is one of the most used treatment options in mitral valve surgery, along with operations on the annular ring and/or leaflets. It is also considered the most gentle approach to structural repair, as it leaves "the door open for future treatments". The new chords, or "neochords", usually consist of a plastic (ePTFE) suture fixed at the leaflet and the papillary muscle to reconnect the structures.
The most gentle method in
structural repair
CHORDART: THE COREMEDIC SOLUTION
First line treatment for mitral valve repair
The ChordArt TMVr System is designed to improve chord repair procedures across all crucial parameters:
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Reduction of patient trauma
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Reduction of procedure time
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Reduction of procedure complexity
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Reduction of operator dependency
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Reduction of recovery time for the patient
The design allows for delivery of the implant via transcatheter and hence allows for intervention in high-risk as well as asymptomatic patients who are not eligible for treatment with the current "Gold Standard" of chord replacement via open-heart surgery.
The ChordArt implant thereby follows nature, anchoring the new chord at the same places as natural chords, resulting in minimal interference with the biological valve structure.
Caution: ChordArt is in the development phase and not approved or cleared by the FDA or any other regulatory body in any region of the world.
